I'm near the end of my first marriage and in answer to the title subject I would say yes. My initial concerns have become reality for us amplified many times.

Telling were her comments about having more respect as a married woman, then later as a mother. Seems that her achieving these milestones were far more important then our relationship.

She is a professional as am I and now we rarely vacation together since her schedule is more important. I have little choice than to find intimacy and closeness with others as I know she does as well.